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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIN1
All Species:
46.97
Human Site:
S111
Identified Species:
73.81
UniProt:
Q13526
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13526
NP_006212.1
163
18243
S111
E
S
L
A
S
Q
F
S
D
C
S
S
A
K
A
Chimpanzee
Pan troglodytes
XP_001161914
174
19574
S111
E
S
L
A
S
Q
F
S
D
C
S
S
A
K
A
Rhesus Macaque
Macaca mulatta
XP_001099116
145
16071
Q94
E
L
I
N
G
Y
I
Q
K
I
K
S
G
E
E
Dog
Lupus familis
XP_542080
163
18285
S111
E
S
L
A
S
Q
F
S
D
C
S
S
A
K
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9QUR7
165
18352
S113
E
S
L
A
S
Q
F
S
D
C
S
S
A
K
A
Rat
Rattus norvegicus
NP_001100171
165
18314
S113
E
S
L
A
S
Q
F
S
D
C
S
S
A
K
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001089028
159
17622
S107
E
S
L
A
S
Q
F
S
D
C
S
S
A
K
A
Zebra Danio
Brachydanio rerio
NP_957042
159
17688
S107
E
S
L
A
S
Q
F
S
D
C
S
S
A
R
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54353
166
18358
S114
D
E
L
A
R
S
Y
S
D
C
S
S
A
K
R
Honey Bee
Apis mellifera
XP_624205
162
18033
S110
A
E
L
A
S
K
Y
S
D
C
S
S
A
K
R
Nematode Worm
Caenorhab. elegans
NP_494393
168
19158
S116
R
E
L
A
K
Q
F
S
D
C
S
S
A
K
R
Sea Urchin
Strong. purpuratus
XP_788025
152
17114
D101
D
L
A
S
T
E
S
D
C
S
S
A
H
K
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SL42
119
12996
S67
E
E
V
A
T
R
V
S
D
C
S
S
A
K
R
Baker's Yeast
Sacchar. cerevisiae
P22696
170
19386
S118
E
A
L
A
K
E
R
S
D
C
S
S
Y
K
R
Red Bread Mold
Neurospora crassa
O60045
182
20596
S130
G
E
L
A
L
T
E
S
D
C
S
S
A
R
K
Conservation
Percent
Protein Identity:
100
93.6
81.5
98.7
N.A.
95.1
95.7
N.A.
N.A.
N.A.
86.5
79.1
N.A.
56
65
57.1
55.2
Protein Similarity:
100
93.6
84
98.7
N.A.
96.9
96.9
N.A.
N.A.
N.A.
93.8
88.9
N.A.
65
74.8
67.2
70.5
P-Site Identity:
100
100
13.3
100
N.A.
100
100
N.A.
N.A.
N.A.
100
86.6
N.A.
60
66.6
73.3
13.3
P-Site Similarity:
100
100
26.6
100
N.A.
100
100
N.A.
N.A.
N.A.
100
93.3
N.A.
73.3
80
73.3
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.1
44.1
50.5
Protein Similarity:
N.A.
N.A.
N.A.
53.9
60.5
63.7
P-Site Identity:
N.A.
N.A.
N.A.
60
60
53.3
P-Site Similarity:
N.A.
N.A.
N.A.
80
73.3
60
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
7
87
0
0
0
0
0
0
0
7
80
0
40
% A
% Cys:
0
0
0
0
0
0
0
0
7
87
0
0
0
0
0
% C
% Asp:
14
0
0
0
0
0
0
7
87
0
0
0
0
0
0
% D
% Glu:
67
34
0
0
0
14
7
0
0
0
0
0
0
7
7
% E
% Phe:
0
0
0
0
0
0
54
0
0
0
0
0
0
0
0
% F
% Gly:
7
0
0
0
7
0
0
0
0
0
0
0
7
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% H
% Ile:
0
0
7
0
0
0
7
0
0
7
0
0
0
0
0
% I
% Lys:
0
0
0
0
14
7
0
0
7
0
7
0
0
80
14
% K
% Leu:
0
14
80
0
7
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
7
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
54
0
7
0
0
0
0
0
0
0
% Q
% Arg:
7
0
0
0
7
7
7
0
0
0
0
0
0
14
34
% R
% Ser:
0
47
0
7
54
7
7
87
0
7
94
94
0
0
0
% S
% Thr:
0
0
0
0
14
7
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
7
0
0
0
7
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
14
0
0
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _